AFP and portal hypertension: For example, in a 50‐year‐old male patient with a solitary HCC ≤3 cm, AFP 10 ng/ml, ALBI grade 1, and absence of portal hypertension, RFS, and HSS were higher when treated by LT than LR, and by LR than LA (Figure 3A) However, if the same patient had two or three multinodular HCC ≤3 cm instead of a single nodule, although LT was better than LR or LA, LA led to similar and better outcomes than LR in terms of RFS and HSS, respectively (Figure 3B).