VIM and viral infectious disease: In addition, the level of HA gene expression was increased significantly in MβCD-treated KO HeLa cells compared with the control group at 6 h of infection, and the difference in the viral HA level was not significant at 30 h after viral infection (Figure 5D), indicating that the disruption of the lipid raft structure in KO-vimentin HeLa cells promoted the replication of the virus in the early stage of infection in the cells.