VIM and viral infectious disease: Based on the above experimental results, to further investigate the role of lipid rafts in H9N2 subtype AIV-infected cells, MβCD was used to disturb the structural integrity of lipid rafts, and it was found that the viral HA gene expression level decreased significantly at 36 h of virus infection in HeLa cells and increased significantly at 6 h in KO-vimentin cells.