Using the combined outcome of COVID-19-related complications that included deep vein thrombosis, secondary bacterial infections, organ failure, ICU access and death, Ruetsch and colleagues found that patients with IFNγ levels at hospital admission lower than 15 IU/mL were associated with more complications and that this correlation was confirmed even after controlling for lymphocyte count [5]. The gene discussed is IFNG; the disease is COVID-19.