IL6 and lymphopenia: Therefore, antimetabolites (e.g., mycophenolate mofetil) are recommended to be held or reduced in particular for patients with lymphopenia (absolute lymphocyte count of less than 700 cells/mL) and calcineurin inhibitors (e.g., tacrolimus and cyclosporine A) should generally be continued as they inhibit interleukin-6 and interleukin-1 pathways [5,91].