Many HPS are rich in galactose and mannose structural units and can specifically recognize the highly expressed asialoglycoprotein receptor (ASGPR) [162] and CD44 receptor [163] in tumor cells, as well as MRs [164], CD206 [165], and TLR-2 [166] in tumor-related macrophages. This evidence concerns the gene ASGR1 and neoplasm.