Pigallocatechin gallate (EGCG), a polyphenol derived from Camellia sinensis (green tea) (Figure 3A), has been shown to have an inhibitory effect on PD-L1 of NSCLC cells through the Janus kinase 2 (JAK2)/STAT1 pathway and AKT pathway (Figure 3B–D) [90]. The gene discussed is CD274; the disease is non-small cell lung carcinoma.