CD8A and neoplasm: In addition, empty liposomes containing DSPE-PEG-maleimide (L-Mals) have been also applied as capturing agents to bind to the DOX-induced tumor-derived protein agents by forming stable thioether bonds and promote the subsequent uptake by APCs such as DCs, resulting in infiltration of more CD8+ T cells and fewer Tregs, which also provides a new insight into liposome utilization.