Ding et al. reported that BRD4 mediates a profibrotic response in activated hepatic stellate cells (HSCs), and inhibition of BRD4 blocks HSC activation into myofibroblasts, while JQ1 treatment attenuates CCl4 (carbon tetrachloride) exposure-induced hepatic fibrosis [113]. Here, BRD4 is linked to Hepatic fibrosis.