Concerning the effect MH on memory impairment and hippocampal neurodegeneration, MH exerted a neuroprotective effect against chronic unpredictable stress-induced memory impairment and cortical neurodegeneration in animals via inhibition of oxidative/nitrergic stress, release of pro-inflammatory cytokines, and downregulation of iNOS and NF-kB. These findings offer an additive view for exploiting MH as an alternative neuroprotectant agent against stress-induced memory dysfunction [38]. Here, NFKB1 is linked to memory impairment.