Malnutrition induced by low protein diet (PM) for 11 weeks or by food-added 0.4 g/kg MSG for 8 weeks into NF pups induced series of complexed inflammatory cascade and brain neurotoxicity mirrored by high IL-1β and TNF-α protein levels in rat serum as depicted in Figure 5A,B. This evidence concerns the gene IL1B and nutritional deficiency disease.