The SUVmax of [68Ga]Ga-PSMA-Q in tumors was higher than those of [68Ga]Ga-PSMA-617 (0.85 ± 0.14, p = 0.42) and [68Ga]Ga-PSMA-11 (0.76 ± 0.18, p = 0.29), with no significant difference, while the tumor-to-muscle ratio of [68Ga]Ga-PSMA-Q was significantly higher than those of [68Ga]Ga-PSMA-617 (59.33 ± 5.72 vs. 20.43 ± 1.06, p < 0.05) and [68Ga]Ga-PSMA-11 (59.33 ± 5.72 vs. 17.95 ± 3.35, p < 0.05), making the tumor more clearly visualized in a clean background. This evidence concerns the gene FOLH1 and neoplasm.