FOLH1 and neoplasm: Due to the high uptake in 22Rv1 tumors and high hydrophilicity, along with rapid elimination from blood and normal organs—including the kidneys—the tumor-to-muscle and tumor-to-kidney ratios of [68Ga]Ga-PSMA-Q were both higher than those of [68Ga]Ga-PSMA-617, [68Ga]Ga-PSMA-11, and the other novel tracers, making the tumor easier to detect from the blood pool, and potentially aiding in the detection of tumors close to the kidneys.