Based on the identification of levels of reactive oxygen species (ROS) and mitochondrial dysfunction, which are involved in the tumoral process, Kim et al. [5] isolated chrysoeriol from Brucea javanica in order to investigate its chemopreventive effect against HT-29 colon cancer, HeLa cervical cancer, and HL-60 leukemia cells using the NF-κB assay, ROS assay, MTP assay, NF-κB, and nuclear factor activated T-cell (NFAT-1) assay. Here, NFKB1 is linked to malignant colon neoplasm.