Furthermore, regular oral administration of SNL at doses of 40 mg/kg and 80 mg/kg for 20 days (day 8th to 28th) resulted in a significant rise in Bcl-2 protein levels in brain homogenate [One-way ANOVA: F(7, 35) = 1.325, p < 0.001] and blood plasma [One-way ANOVA: F(7, 35) = 1.968, p < 0.001] samples to the OUA-treated BD like rats. This evidence concerns the gene BCL2 and Behcet disease.