IL1B and Behcet disease: Similarly, chronic oral treatment with SNL40 mg/kg and SNL80 mg/kg remarkably decreased the level of IL-1β in brain homogenate [One-way ANOVA: F(7, 35) = 0.348, p < 0.001] and blood plasma samples [One-way ANOVA: F(7, 35) = 0.691, p < 0.001], as opposed to the OUA toxin administered BD like rats.