Through the sequence of UCSC hg19 (exome) and the reference gene homo sapiens angiotensin-converting enzyme 2 (NG_012575.1:6110-46037) on chromosome X, five ACE2 SNPs (rs4646142 G > A or C, rs2048683 T > A or G, rs4240157 C > G or T, rs6632677 G > C, rs2074192 C > T) known to be associated with human cardiovascular diseases and diabetes were examined. Here, ACE2 is linked to cardiovascular disorder.