SOD1 and COVID-19: It was found that the previously demonstrated enhancement in ROS generation in plasma of COVID-19 patients is accompanied by a decrease in the activity of the basic enzymes responsible for the dismutation of the superoxide anion radicals; (Cu,Zn-SOD—SOD-1 and Mn-SOD—SOD-2), including patients who survived and considerably stronger patients who have died (Figure 1).