CREB1 and non-small cell lung carcinoma: Hye-Sook Seo found that the expression levels of mRNA and CREB and phosphorylated CREB (pCREB) were significantly higher in most of the non-small cell lung cancer (NSCLC) cell lines than in the normal human tracheobronchial epithelial (NHTBE) cells and adjacent normal lung tissue, respectively [39].