Several antigens or receptors are expressed on the surface of the membrane of tumor cells, such as human epidermal growth factor receptor 2+ (HER2+), epidermal growth factor receptor (EGFR), CD20, prostate-specific membrane antigen (PSMA), vascular endothelial growth factor (VEGF), mucin 1 (MUC1) and tumor necrosis factor (TNF). The gene discussed is ERBB2; the disease is neoplasm.