A2780/CP is a Cisplatin-resistant ovarian cancer cell line which is derived from A2780, Cisplatin-sensitive ovarian cancer cell line., HIF-1α is down-regulated in A2780 and PEO1 cell line after Cisplatin treatment and the cancer cells undergo apoptosis, whereas Cisplatin sensitivity restores after HIF-1α knockdown and induces apoptosis in Cisplatin-resistant cell line A2780/CP and PEO4. Here, HIF1A is linked to ovarian carcinoma.