Moreover, elevated IL-8 is characteristic of multiple EBV-associated diseases, such as NPC, gastric cancer, hemophagocytosis, chronic periodontitis, multiple sclerosis, murine models of NK/T lymphoma, infectious mononucleosis (IM), and post-IM chronic fatigue syndrome [49,50,51,52,53,54]. This evidence concerns the gene CXCL8 and chronic periodontitis.