We considered the level of hs-cTnI increase more than 5 times to be the diagnostic criteria for diagnosing NSTEMI and results were alarming: almost every fifth patient had hs-cTnI increased by more than 5 times followed by ischemic changes in ECG, typical symptoms or obstructive CAD confirmed by CAG. The gene discussed is TNNI3; the disease is coronary artery disorder.