Moreover, studies have reported that there is a formation of neutrophil extracellular traps (NET) and monocyte recruitment within the lung micro-vessels in COVID-19 patients with severe disease causing leakage due to endothelial cell dysfunction, leading to pulmonary edema and disseminated intravascular coagulation manifested by raised levels of D-dimers, lactate dehydrogenase (LDH), ferritin and increased duration of prothrombin time (PT), activated partial thromboplastin time (aPTT), international normalized ratio (INR) and raised levels of platelet count [6,7,8,9,10,11]. The gene discussed is F2; the disease is edema.