The expression of somatostatin receptors type 2 and 3 has been described in gonadotroph tumors [99] but does not necessarily imply therapeutic efficacy, as proven by the case of increased tumor uptake at Indium 111-labeled octreotide scintigraphy in a FGA but complete lack of therapeutic effect of octreotide on either tumor secretion or size [100]. The gene discussed is SSTR2; the disease is neoplasm.