In contrast, Tff3-deficient (Tff3-/-) mice generated on a mixed genetic background (C57BL/6J/Sv129) showed improved utilization of glucose and enhanced insulin sensitivity with increased formation of small lipid vesicles in the liver compared with wild-type (WT) controls but without obvious signs of hepatic steatosis [17]. Here, TFF3 is linked to Hepatic steatosis.