TFF3 and metabolic dysfunction-associated steatohepatitis: Progression of NAFLD to more severe forms due to chronic dietary exposure, e.g., nonalcoholic steatohepatitis (NASH), is characterized by an increased inflammatory state in the liver [65,66] The role of Tff3 in the immune response has been studied mainly in the context of gastrointestinal inflammatory pathologies, where it has been shown to elicit both pro- and anti-inflammatory activities [4].