IGF1R and colorectal carcinoma: IGF1R depletion/inhibition sensitizes CRC cells to radiotherapy (converting them to radiosensitive), as shown in HT-29 and SW480 cell lines where IGF1R was inhibited by NVP-ADW742 [213] and in HT-29, SW480 and DLD-1 cells pretreated with BMS-754807 [214].