An analysis of 40 single-nucleotide polymorphisms (SNPs) in 40 genes of 503 T2DM patients vs. 580 healthy controls on a Sequenom platform identified SNPs in the CAT, FTO and UCP1 genes associated with the retinopathy and nephropathy complications of T2DM [170]. The gene discussed is UCP1; the disease is type 2 diabetes mellitus.