Next, the GScore was evaluated in CCA cell lines and correlated with mutations in HRR-related genes ARID1A, ATM, ATRX, BAP1, BARD1, BLM, BRCA1, BRCA2, BRIP1, CHEK2, CHEK1, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCL, MRE11, NBN, PALB2, RAD50, RAD51, RAD51B, and RAD51D (Figure 1b, Table S2). The gene discussed is BAP1; the disease is cholangiocarcinoma.