However, they observed a positive correlation between SOD activity and 8-iso-PGF2α concentration in urine [96], whereas, Kostić et al. observed a statistically significant decrease in erythrocyte GPx activity after an acute exercise test on the cycloergometer in peripheral blood in 40 hypertensive patients (51.19 ± 8.37 years) [97]. Here, SOD1 is linked to Hypertension.