Similarly to AR gene expression in human GBM tissues, expressions of PARD3B mRNA in most TCGA cancers, including breast invasive carcinoma (BRCA), CESC, HNSC, KICH, KIRC, KIRP, LUAD, LUSC, READ, THCA, THYM, and UCEC, were downregulated (Figure 2C). The gene discussed is PARD3B; the disease is cancer.