The molecular mechanism of association of the preeclampsia with hyperlipidemia is not well understood.Therefore, the purpose of our study was to determine the mRNA and protein expression of the ABCA1 and LXRA/LXRB genes in the placenta of late-onset preeclamptic women compared to normotensive, healthy Polish women with uncomplicated pregnancies. The gene discussed is ABCA1; the disease is preeclampsia.