NPPB and pulmonary embolism: The European Society of Cardiology (ESC) guidelines categorize acute PE as being at low, intermediate, and high risk of 30 days mortality based on hemodynamic status, bedside clinical scoring systems such as the Pulmonary Embolism Severity Index (PESI) and simplified PESI (sPESI) [10,11], RV function on imaging [12], and cardiac biomarkers (i.e., troponin and brain-type natriuretic peptide) [13,14] with a view to therapeutic decision making [3].