The secretion of 12 cytokines (IL2, IL4, IL5, IL6, IL10, IL12, IL13, IL17A, INFg, TNFa, G-CSF, TGFβ1) was measured by ELISA test in the supernatant of 6 samples of C-MSCs and 9 samples of AD-MSCs, both at baseline and after 16 weeks of treatment with Dupilumab. The gene discussed is IL4; the disease is Alzheimer disease.