Other suggested biomarkers which may predict the development of AD in infancy include elevated umbilical cord serum IgE and TARC/CCL17 levels [68,69], epidermal thymic stromal lymphopoietin protein (TSLP) expression [70], decreased level of natural moisturizing factor (NMF) and measurement of transepidermal water loss (TEWL) in newborns’ skin [71,72]. Here, IGHE is linked to Alzheimer disease.