AKT1 and hydrops fetalis: For example, lncRNA XLOC_008679 could regulate the HF cycle by KRT35 in anagen [22], lncRNA H19 maintained the HF-inducing ability through the Wnt/β-catenin signaling pathway [23], and lncRNA5322 promoted HFSC proliferation and differentiation through the PI3K-AKT signaling pathway [24].