TLR4 and Cirrhosis: Regarding the secondary end points, the multivariable analysis including gender, age, CTP and MELD scores, TLR4 mutations and cause of cirrhosis, all-cause death showed a statistically significant correlation with CTP (odds ratio (OR) 1.50 (95% confidence interval (CI) 1.21–1.86), p value 0.0002), while liver-related deaths were also correlated with CTP (OR 1.33 (95% CI 1.1–1.65), p value 0.0089).