TLR4 and hepatocellular carcinoma: From the 52 patients with HCC, 10 (19.2%) had TLR4 mutations (7 Asp299Gly, 2 Thr399Ile and 1 both Asp299Gly and Thr399Ile), while from the 208 patients with no HCC, TLR4 mutation was found in 62 (29.8%) (55 Asp/299Gly, 6 Thr399Ile and 1 both Asp299Gly and Thr399Ile) (p value 0.127).