CETP and coronary artery disorder: A meta-analysis by Nomura et al. of nearly 60,000 participants from 12 case-control studies found that, compared with non-carriers, carriers of CETP truncating variants had significantly higher HDL-C (22.6 mg/dL [0.58 mmol/L]), lower LDL-C (−12.2 mg/dL [−0.32 mmol/L]) and TG (−6.3%), and reduced risk of coronary heart disease (CHD) (summary odds ratio 0.70; 95% CI 0.54–0.90) [40].