CETP and cardiovascular disorder: This is an important concept for the development of new CETP inhibitors, such as obicetrapib, the only CETP inhibitor still in phase 3 clinical development, which has been shown to substantially lower LDL-C and apoB and is being investigated in the ongoing Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients with Cardiovascular Disease (PREVAIL) [26].