Specifically, using PBMCs collected <48 h from admission, we previously defined four genes (ARG1, IL10, NOS2, and IL12) that when aggregated into a ratio of (ARG1 + IL-10)/(NOS2 + IL-12), their correlation with patient outcomes was most significant whereby outcomes include lung injury, infection, autograft failure, and death [16]. This evidence concerns the gene IL10 and infection.