PPARG and infection: A key result of metabolic and immune re-programming by PPARγ, is the activation of anti-inflammatory signals, such as the cytokine interleukin-10 (IL-10), promotion of restorative processes, such as the polarization of macrophages and neutrophils into alternatively activated type-2 anti-inflammatory macrophage (M2) and neutrophil (N2) populations, and subsequent susceptibility to infection.