Another mechanism regulating NDRG2 expression is mediated by microRNAs (miRNAs); miRNA-181c [20], miR-454 [21], miR-483 [22], miR-650 [23], and et al. NDRG2 expression level is positively correlated with tumor differentiation and overall survivals, but negatively correlated with tumor invasion, tumor recurrence, lymph node metastasis, and TNM staging in various tumor patients (Table 1). Here, NDRG2 is linked to neoplasm.