TNF and acute respiratory distress syndrome: Indeed, the overexpression of miR-124 or the silencing of MAPK14 could downregulate the expression of inflammatory cytokines, both those that induce (TNF-α, IL-6, IL-1β) and those that inhibit inflammation (IL-10) in ALI mice, thus inhibiting or limiting the degree of tissue damage and pulmonary edema due to an inflammatory response.