DYRK1A and pancreatic neoplasm: On the other hand, DYRK1A was highly expressed in lung and pancreatic cancer cells, and that its protein level was positively correlated with that of STAT3, c-MET and EGFR (Table 1) as it was found that DYRK1A siRNA could suppress the levels of EGFR and MET receptor tyrosine kinases [46,56,57,58].