In addition, CD147 inhibition by AC-73 resulted in a potent growth inhibitory effect in leukemia cells by deactivating the ERK/STAT3 pathway and activating autophagy, as well as increasing the chemosensitivity of leukemia cells to the conventional antileukemia drugs arabinosylcytosine and arsenic trioxide [102]. The gene discussed is STAT3; the disease is leukemia.