Additionally, 72.7% (8/11) of the Gleason 10 PCa tissues had a higher IHC score, 64.3% (18/28) of the Gleason 9 PCa tissues, 56.5% (13/23) of the Gleason 8 PCa tissues had a higher IHC score, 31.8% (7/22) and 33.3% (2/6) of Gleason 7 and 6 PCa tissues had high TRIM25 IHC score (Figure 5C). This evidence concerns the gene TRIM25 and posterior cortical atrophy.