We studied the PI3K-Akt-NF-κB pathway in salivary gland adenoid cystic carcinoma, using the UM-HACC-2A cell line, and our data indicate that activated Akt (p-akt) is upregulated in the Ganetespib-treated cells. Here, AKT1 is linked to salivary gland adenoid cystic carcinoma.