PEMT and metabolic dysfunction-associated steatotic liver disease: Although a previous study reported a threefold higher risk of NAFLD in lean Asian Indian carriers of the rs7946 risk genotype [21], we did not find evidence for statistically significant association between any of the PEMT variants and NAFLD in 21 Caucasians with a lean BMI (i.e., BMI ≤ 25 kg/m2).