PEMT and metabolic dysfunction-associated steatotic liver disease: In pairwise comparisons of PEMT expression levels in participants with normal liver histology, we found significantly reduced levels of hepatic PEMT expression in NAFLD patients with inflammation (β = −1.476; p = 0.015) and fibrosis (β = −1.504; p = 0.013), but not with steatosis, although a similar trend was observed (β = −0.550; p = 0.222) (Figure 1B).