TG and hypothyroidism: The general clinical presentation of congenital iodide transport defect, an autosomal recessive disorder due to impaired iodide accumulation in the thyroid follicular cell, includes a variable degree of hypothyroidism, reduced to absent radioiodide accumulation in a normal to hyperplastic eutopic thyroid gland, a low saliva-to-plasma iodide ratio, and normal to increased thyroglobulin (TG) serum levels [4,5,6,7].