Regarding inflammation, BDC pretreatment in PBMCs of AD patients showed that curcumin decreases the NF-κB, BACE1, and Toll-like receptor mRNA levels and upregulates the mRNA levels of mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase (MGAT3) and the vitamin D receptor (VDR) [16,21,30]. The gene discussed is NFKB1; the disease is Alzheimer disease.