In addition, the same study [36] illustrated that reduced LVEF and raised N terminal pro-brain natriuretic peptide (NT-proBNP) levels correlated with increased levels of IL-37 before PCI, thereby independently anticipating in-hospital MACEs, acute HF, cardiac death, non-fatal myocardial infarction and target lesion revascularization (TLR). The gene discussed is NPPB; the disease is myocardial infarction.