In addition, a polypeptide confirmed to be the product of the orf138 gene using antibodies against a glutathione S-transferase-ORF138 fusion protein was only found in sterile-plant mitochondria isolated from B. napus with Ogura CMS, which further confirmed that orf138 was the sterility gene in Ogura CMS [17,18]. Here, HPGDS is linked to congenital myasthenic syndrome.