Concomitantly, the expression of the antiapoptotic B-cell lymphoma 2 (Bcl-2) protein was increased [74,75] On the other hand, using experimental models of ischemia in vivo and in vitro, allicin decreased intracellular calcium concentrations and Bax expression, in contrast, Bcl-2 was increased, resulting in the increase in cell viability and reduction in apoptotic index [76]. The gene discussed is BCL2; the disease is ischemia.