HMOX1 and chronic kidney disease: In an experimental model of chronic kidney disease (CKD), allicin upregulated nuclear factor erythroid 2—related factor 2 (Nrf2), catalase (CAT), superoxide dismutase (SOD), and heme oxygenase-1 (HO-1), which was associated to decrements in oxidized proteins and lipid peroxidation in kidney tissue, improving the renal function [72].