Rg3 also modulated EMT-related molecules, such as activations of E-cadherin and Snail and suppressions of N-cadherin, Vimentin, and zing-finger E-box-binding homeobox factor (ZEB) 1 in five different cell lines: lung, nasopharynx, colorectum, and bone tumor, respectively. Here, VIM is linked to bone neoplasm.