Altered phosphorylation of FAK and the protein tyrosine kinase Src is observed in human brains of AD patients [12], and alterations in tyrosine phosphorylation in brains of patients with the disease lead to increased FAK and Tau (MAPT) phosphorylation in response to amyloid β (Aβ) exposure [13]. The gene discussed is PTK2; the disease is Alzheimer disease.