RPS6KB1 and Alzheimer disease: The 70 kDa S6 kinase (p70S6K; T252, +286% CFC) plays a critical role in regulating cell cycle, cell growth, and cell proliferation [59], and can be activated by the PI3K pathway via PDK1 which showed increased expression in our assay or by Aβ deposition that is enhanced in AD [60].