In addition to intercellular communication, several roles have been hypothesized for CD34+SCs/TCs, including control and organization of the extracellular matrix, structural support, endocytosis, creation of tissular microenvironments, guidance to cell migration, contribution of scaffolds, immunomodulation, neurotransmission, control and regulation of other cell types, stem cell modulation, and participation in angiogenesis, regeneration, repair, and tumor stroma formation [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21]. Here, CD34 is linked to neoplasm.