Therefore, a better understanding of the behavior, function, and modulation of pericytes, CD34+SCs/TCs, and derived cells, genes, and signals pathways involved in these angiogenic processes, as well as of those that regulate the transition from sprouting to intussusceptive angiogenesis, is of interest for the development of new antiangiogenic therapies and to prevent tumor recurrences [220,221,222]. This evidence concerns the gene CD34 and neoplasm.