With regard to NBCe1 protein abundance, as shown in Figure 6B, although hypoxia-induced significant NBCe1 upregulation in MES-like hypoxia-dependent GBM cells (1.15 ± 0.05-fold; Figure 5B, lane 2) was decreased during chemical hypoxia in combination with extracellular pH of 6.8 (0.97 ± 0.07-fold; Figure 6B, lane 3) no significant differences were detected in hypoxia in the presence or absence of extracellular acidosis (Figure 6B, lanes 2 and 3). Here, SLC4A4 is linked to glioblastoma.